Inventor Name
Moore-Stein Protein Sequencer
Repository
National Museum of American History
Smithsonian Institution
Archives Center
P.O. Box 37012
MRC 601/Room 1100
Washington, DC 20013-7012
202-633-3270
http://americanhistory.si.edu/archives
Physical Description
0.50 cu. ft.: 2 boxes.
Summary
The first complete chemical analysis of a protein's primary structure was done on a small protein, insulin, by Frederic Sanger at Cambridge University for which he received the first of his two Nobel Prizes in 1958. The second protein structure to be completely analyzed was ribonuclease, done in the U.S. by Stanford Moore and William Stein at Rockefeller University, 1960. This videohistory documents the Moore-Stein Protein Sequencer. The sequencer enabled automatic analysis of protein structure and was the forerunner of the automated instruments essential to modern biotechnology.