National Museum of American History
P.O. Box 37012
MRC 601/Room 1100
Washington, DC 20013-7012
0.25 cu. ft.: 1 box
In the 1970s when Civin began stem cell research, little was known about progeniters, the cells of all other blood lineages. Civin thought that stem cells had their own identifying surface proteins. To test this, he immunized mice with leukemia cells, some of which he supposed might have that peculiar protein and then harvested the resulting immunoglobulins and reproduced them as monoclonal antibodies. In 1981, Civin discovered an antibody that bound to 1% of marrow cells. Original videos documenting Curt I. Civins's discovery of the cell surface protein that makes stem cell selection possible; and interviews with Kenneth Kinsler and Bert Vogelstein.